2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Drug Metabolite

Drug Metabolite

Drug Metabolite

Related Products

PDF 3.95 MB

Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-169045
    (±)13,14-EDT
    		Control
    (±)13,14-EDT is an oxylipin and a metabolite of Adrenic acid (HY-W013215) formed via the cytochrome P450 (CYP) pathway.
    (±)13,14-EDT
  • HY-W970291
    N-Acetyl-S-(2-hydroxypropyl)-l-cysteine
    N-Acetyl-S-(2-hydroxypropyl) -l-cysteine is a metabolite of propylene oxide and is used as the biomarker of propylene oxide exposure. It is significantly positively associated with diabetes and dyslexia.
    N-Acetyl-S-(2-hydroxypropyl)-l-cysteine
  • HY-W099331R
    Monoethylglycinexylidide hydrochloride (Standard)
    Benfuracarb (Standard) is the analytical standard of Benfuracarb. This product is intended for research and analytical applications. Benfuracarb is a broad-spectrum carbamate insecticide with crop protection activity. Benfuracarb is used to control springtails, aphids, and other pests, typically on sugar beet crops. Benfuracarb exhibits toxicity to humans and aquatic organisms. Benfuracarb exposure to zebrafish embryos resulted in a reduction in the body length of zebrafish larvae. Superoxide dismutase (SOD) activity was significantly increased after Benfuracarb treatment. Benfuracarb also interfered with the transcriptional levels of marker genes associated with early embryonic development.
    Monoethylglycinexylidide hydrochloride (Standard)
  • HY-W154117
    2,2-Dichloro-1,1-ethanediol
    2,2-Dichloro-1,1-ethanediol is a metabolite of the insecticides Dichlorvos (HY-B1312) and Trichlorphon, is mutagenic in the Salmonella/microsome test.
    2,2-Dichloro-1,1-ethanediol
  • HY-B1259R
    6-Acetamidohexanoic acid (Standard)
    6-Acetamidohexanoic acid (Acexamic acid; 6-Acetamidocaproic acid) (Standard) is the analytical standard of 6-Acetamidohexanoic acid. This product is intended for research and analytical applications. 6-Acetamidohexanoic acid (Acexamic acid; 6-Acetamidocaproic acid) is a metabolite of Hexamethylene bisacetamide (HMBA) (HY-124284) with anti-pulmonary fibrosis activity. 6-Acetamidohexanoic acid does not induce differentiation of human promyelocytic leukemia cells, but is taken up by such cells. 6-Acetamidohexanoic acid serves as a carboxylic acid substrate component for constructing carboxylesterase-responsive near-infrared phototheranostic probes. 6-Acetamidohexanoic acid is applicable to research related to pulmonary fibrosis, refractory hypoxemia and cervical cancer.
    6-Acetamidohexanoic acid (Standard)
  • HY-W720429
    2,5-Diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine
    2,5-Diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine is a metabolite in the biosynthesis pathway (purine metabolism process) of Riboflavin (HY-B0456).
    2,5-Diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine
  • HY-133992
    Fensulfothion sulfone
    Fensulfothion sulfone is a metabolite of the organophosphorus insecticide fensulfothion.
    Fensulfothion sulfone
  • HY-137772R
    Captopril EP Impurity E (Standard)
    Captopril EP Impurity E (Standard) is the analytical standard of Captopril EP Impurity E. This product is intended for research and analytical applications. Captopril EP Impurity E is an impurity of Captopril. Captopril (SQ-14534), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM).
    Captopril EP Impurity E (Standard)
  • HY-121273
    Diclofop
    Diclofop (Dichlorfop acid) is an acetyl-CoA carboxylase (ACC) inhibitor. Diclofop is also the major metabolite of the herbicide Diclofop-methyl (HY-136367). Diclofop exhibits antimalarial activity with an IC50 of 210 μM against P. falciparum.
    Diclofop
  • HY-162297
    4-(Sulfooxy)benzoic acid
    4-(Sulfooxy)benzoic acid is a sulfated phenolic acid found in C. elegans. 4-(Sulfooxy)benzoic acid is a metabolite of ethyl para-hydroxybenzoate and several flavonoids.
    4-(Sulfooxy)benzoic acid
  • HY-169851
    JANEX-1-M
    JANEX-1-M is a metabolite of JANEX-1 (HY-15508). JANEX-1 is a JAK3 specific inhibitor, which can effectively inhibit mast cell degranulation and the release of pro-inflammatory mediators.
    JANEX-1-M
  • HY-133926
    5-O-Desmethyl donepezil
    5-O-Desmethyl donepezil is a metabolite of Donepezil (HY-14566). 5-O-Desmethyl donepezil is an inhibitor for hERG channel with an IC50 of 1.5 μM.
    5-O-Desmethyl donepezil
  • HY-101397R
    Allopurinol riboside (Standard)
    Cholic acid (Standard) is the analytical standard of Cholic acid. This product is intended for research and analytical applications. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid is orally active.
    Allopurinol riboside (Standard)
  • HY-W653737
    N-Nitrosoglyphosate
    N-Nitrosoglyphosate is the nitrosamine degradation product of glyphosate herbicidee.
    N-Nitrosoglyphosate
  • HY-125594
    T-1095A
    T-1095A is an active metabolite of T-1095 (HY-106158) (an SGLT inhibitor).
    T-1095A
  • HY-172833
    (±)19(20)-DiHDTE
    (±)19(20)-DiHDTE is a an oxidized lipid compound. (±)19(20)-DiHDTE is the product formed when docosapentaenoic acid (DPA) is oxidatively metabolized by cytochrome P450.
    (±)19(20)-DiHDTE
  • HY-W585928
    Di-o-cresyl phosphate
    Di-o-cresyl phosphate is a urinary metabolite of tri-o-cresyl phosphate (HY-W011086), o,o,m-tricresyl phosphate, and o,o,p-tricresyl phosphate, and serves as a biomarker for monitoring exposure to ortho-isomers of tricresyl phosphate. Di-o-cresyl phosphate is not a metabolite of mono-o-tricresyl phosphate. Di-o-cresyl phosphate can be used in studies related to delayed neuropathy (OPIDN).
    Di-o-cresyl phosphate
  • HY-N2481R
    Oroxylin A-7-O-glucuronide (Standard)
    Oroxylin A-7-O-glucuronide (Standard) is the analytical standard of Oroxylin A-7-O-glucuronide (HY-N2481). This product is intended for research and analytical applications. Oroxylin A-7-O-glucuronide (oroxyloside) is an orally active flavonoid glucuronide and metabolite of Oroxylin A (HY-N0560). Oroxylin A-7-O-glucuronide can be extracted from the dried root of Scutellaria baicalensis. Oroxylin A-7-O-glucuronide exhibits prolyl oligopeptidase inhibitory activity. Oroxylin A-7-O-glucuronide inhibits the JNK pathway, upregulates PPARγ, and inhibits NF-κB p65 nuclear translocation. Oroxylin A-7-O-glucuronide reduces cytokine (IL-1β, IL-6) production. Oroxylin A-7-O-glucuronide exhibits anti-angiogenic, anti-tumor (glioma, liver cancer), anti-inflammatory, and hepatoprotective activities.
    Oroxylin A-7-O-glucuronide (Standard)
  • HY-N9484S
    Menthofuran-13C2
    Menthofuran-13C2 is 13C labeled Menthol (HY-N1369). Menthol is an analgesic and TRPM8 modulator. TRPM8 is a cold temperature sensing ion channel, and Menthol can regulate TRPM8 to exert analgesic and anti-irritation mechanisms. Menthol stimulates cold receptors and produces a cooling sensation by inhibiting Ca++ currents in neuronal cell membranes. Menthol also improves oral nicotine rejection in mice.
    Menthofuran-<sup>13</sup>C<sub>2</sub>
  • HY-N9389
    Ginsenoside C-Y
    Ginsenoside C-Y (Ginsenoside Y) is a metabolite of Ginsenoside Rb2 (HY-N0040). Ginsenoside C-Y exhibits anti-photoaging and anti-melanogenesis properties.
    Ginsenoside C-Y
Cat. No. Product Name / Synonyms Application Reactivity